Serving mainly as Captain Forrest's woman, Sato had previously been involved with Jonathan Archer but left him for Forrest when he was promoted to a position of higher power. When Archer briefly took command of the Enterprise in 2155 she gravitated towards him again as he was then the more powerful. While making advances towards Archer, she made an effort to stab him with a dagger, but her attempt was thwarted. Later, after she and Archer had made love, she casually proposed that T'Pol, not Tucker, might have had a hand in sabotage aboard the ship, making Archer realize that he should have suspected T'Pol as well. However, T'Pol had already led an insurgency to restore Forrest to command.
Sato assisted Jonathan Archer in using the Defiant to gain power. However, before the Defiant could make it to Earth, she seduced Archer's personal guard Travis Mayweather into conspiring to kill Archer by poisoning. Sato subsequently took command of the Defiant, proclaimed herself "Empress Sato", and ordered Fleet Admiral Gardner to surrender and stand by for instructions, or she would open fire on Earth. (ENT: "In a Mirror, Darkly")
- Considering the discrepancy in technology between the Defiant and Earth, one is left to assume that she won and became Empress, but that's far from clear.