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Jennifer Sisko was an Klingon-Cardassian Alliance scientist who betrayed her people and joined the Terran Rebellion, shortly before her death.


Jennifer was married to Benjamin Sisko, though they separated in 2366. In 2371 Benjamin Sisko was able to convince Jennifer to switch sides and join the Terran Rebellion. (DS9: "Through the Looking Glass")

In 2372, Jennifer abducted Jake Sisko from station Deep Space 9 in order to lure Benjamin Sisko of the mirror universe to this universe. Her attempt was successful and Sisko helped the Terran Rebellion to build a Defiant-class vessel for Terok Nor. While Jake was on Terok Nor, he and Jennifer grew close and became almost like family despite protests by Benjamin Sisko. While attempting to take Jake back to his universe, Jennifer was shot by Kira Nerys, who had escaped Terran imprisonment. Jennifer died in Jake's arms. (DS9: "Shattered Mirror")